By John Glassie
A Scientific American Best technology booklet of 2012
An Atlantic twine most sensible ebook of 2012
A New York instances booklet Review Editor's Choice”
The fascinating” (The New Yorker) tale of Athanasius Kircher, the eccentric scholar-inventor who was once both a superb genius or a crackpot . . . or a little both.
The pursuits of Athanasius Kircher, the mythical seventeenth-century priest-scientist, knew no bounds. From optics to track to magnetism to medication, he provided up innovations and theories for every thing, and so they made him well-known throughout Europe. His celebrated museum in Rome featured magic lanterns, conversing statues, the tail of a mermaid, and a brick from the Tower of Babel. Holy Roman Emperors have been his consumers, popes have been his buddies, and in his spare time he collaborated with the Baroque grasp Bernini.
yet Kircher lived in the course of an period of radical transformation, within which the previous method of knowledgewhat he referred to as the art of knowing” used to be giving strategy to the clinical process and sleek idea. A guy of Misconceptions traces the increase, good fortune, and eventual fall of this attention-grabbing personality as he tried to return to phrases with a altering world.
With humor and perception, John Glassie returns Kircher to his rightful position as considered one of history’s so much unforgettable figures.
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Extra resources for A Man of Misconceptions: The Life of an Eccentric in an Age of Change
15 Chapter 2: Physiologic Goals of Mechanical Ventilation Permissive hypercapnia may adversely affect oxygenation i n some patients. Elevated Paco2 and acidosis shift the oxyhemoglobin dissociation curve to right. This decreases the affinity of hemoglobin for oxygen, decreasing oxygen loading in the lungs but facilitating unloading of oxygen at t he tissues. As illustrated by the alveolar gas equation, an increase in alveolar P co2 results in a decrease in alveolar Po2• For each Paco2 rise of 1 mm Hg, the Pao2 decreases by about 1 mm Hg.
Classification of ventilator modes: update and proposal f or implementation. ) is reached. Pressure-controlled ventilation is pressure limited because the pressure limit is reached before inspiration ends. F or some ventilators, the inspiratory flow, inspiratory time, and tidal volume are set separately. In this case, the ventilator is volume limited because tidal volume is delivered before inspiration ends. 46 Port 1 : Principles of Mechanical Ven tilation Table 5-2 Ventilation Modes Identified by Breathing Patterns Breath-control variable Breath sequence Acronym Volume Continuous mandatory ventilation Intermittent mandatory ventilation VC-CMV VC-IMV Pressure Continuous mandatory ventilation Intermittent mandatory ventilation Continuous spontaneous ventilation PC-CMV PC-IMV PC-CSV (ie, pressure support ventilation Adapted from CHATBURN RL.
Anesthesiol Clin. 2012;30:573-579. Calzia E, Asfar P, Hauser B, Matejovic M, et al. Hyperoxia may be beneficial. Crit Care Med. 2010;38:S559-S568. de Prost N, Ricard JD, Saumon G, Dreyfuss D. Ventilator-induced lung injury: historical perspectives and clinical implications. Ann Intensive Care. 2011;1:28. Della Rocca G, Coccia C. Acute lung injury in thoracic surgery. Curr Opin Anaesthesiol. 2013;26:40-46. Gattinoni L, Protti A, Caironi P, Carlesso E. Ventilator-induced lung injury: the anatomical and physiological framework Crit Care Med.
A Man of Misconceptions: The Life of an Eccentric in an Age of Change by John Glassie